The Lysak Lab

About us

We investigate genome evolution across the plant kingdom at different levels of complexity:  

  • DNA sequences (NGS-based genome analysis)
  • Chromosomes (chromosome rearrangements, karyotype evolution)
  • Genomes (genome collinearity, polyploidy)
  • Species (speciation, phylogenomics)


Genome evolution in crucifers (Brassicaceae) is our leading research theme. We are analyzing the incidence, mechanisms and rate of chromosome rearrangements, sequence structure of chromosome breakpoints, modes of centromere shift and elimination, evolution of repetitive sequences, and reconstructing ancestral genomes. We are testing causal links between whole-genome duplication events, karyotypic variation and species radiations.


If you are interested in joining the lab, please contact us!



The Aquilegia paper higlighted at CEITEC's website

Our joint paper about the eleven sequenced columbine genomes and one odd...

The Ricotia story published in Plant Journal - recurrent origin of a fusion chromosome!

The ancestral Ricotia genome was formed by a rare inter-clade hybridization event, followed by cladogenesis accompanied by...

Teri Mandáková awarded for outstanding scientific results

Teri was award for extraordinary research results achieved by scientists in the age group under 35 from the Rector of Masaryk...

Post-polyploid diploidization and diversification through dysploid changes

Our review on the role of chromosomal rearrangements and descending...