The Lysak Lab

About us

We investigate genome evolution across the plant kingdom at different levels of complexity:  

  • DNA sequences (NGS-based genome analysis)
  • Chromosomes (chromosome rearrangements, karyotype evolution)
  • Genomes (genome collinearity, polyploidy)
  • Species (speciation, phylogenomics)


Genome evolution in crucifers (Brassicaceae) is our leading research theme. We are analyzing the incidence, mechanisms and rate of chromosome rearrangements, sequence structure of chromosome breakpoints, modes of centromere shift and elimination, evolution of repetitive sequences, and reconstructing ancestral genomes. We are testing causal links between whole-genome duplication events, karyotypic variation and species radiations.


If you are interested in joining the lab, please contact us!



Ancestral building blocks of crucifer genomes revisited

We revisited the concept of the Ancestral Crucifer Karyotype (ACK) and the definition of a revised set of 22 conserved genomic...

chromDraw graphic tool for karyotype visualization

Basic features of the chromDraw tool are described in our recent paper published in Chromosome Research.

TheBoechera paper and Lysak lab highlighted in Lab Times's journal club

Plant Cytogenomics in Brno, Czech Republic: Treading in Mendel’s Genomic Footsteps

Insight into evolution of the Noccaea /Thlaspi caerulescens genome

In the September issue of Plant Physiology, we describe the comparative genome structure of the Alpine...

Our paper on chromosome evolution in Boechera highlighted in Trends in Plant Science

A Spotlight article written by Marcus Koch (University of Heidelberg) can be downloaded from the link below.